Glossary entry

Spanish term or phrase:

umbral de retirada de la pata

English translation:

paw withdrawal threshold (PWT)

Added to glossary by sebaspedlp
Jan 16, 2022 00:44
2 yrs ago
18 viewers *
Spanish term

umbral de retirada de la pata

Spanish to English Medical Medical: Pharmaceuticals
hola estoy haciendo la traducción de párrafos de un ensayo clínico y me encuentro con este parrafo:

Se realizaron el umbral de retirada de la pata a la estimulación mecánica y las pruebas de latencia de retirada térmica. Después de la administración, se aislaron las neuronas de ratas L4, L5 de la raíz dorsal (DRG) de las ratas. Además, los plásmidos subtipo de canales activados por hiperpolarización activados por nucleótidos cíclicos (HCN, por sus siglas en inglés) se transfectaron en células de riñón embrionario humano (HEK).

mi intento
The Paw withdrawal threshold to mechanical stimulation and thermal withdrawal latency tests were performed

gracias
Proposed translations (English)
3 +2 paw withdrawal threshold (PWT)

Proposed translations

+2
1 hr
Selected

paw withdrawal threshold (PWT)

The point at which the withdrawl or retraction reflex is in accomplished

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Note added at 1 Stunde (2022-01-16 02:23:43 GMT)
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Parece que era traducido algun tiempo recente de la citacion ResearchGate.net This study was designed to examine the effect and mechanism of dexmedetomidine (Dex) on neuropathic pain (NP). The NP model was established by performing chronic sciatic nerve constriction injury (CCI). Seven days after CCI surgery, the rats were injected intraperitoneally with Dex, ZD7288 (an HCN channel inhibitor), and saline, respectively. The paw withdrawal threshold to mechanical stimulation and the thermal withdrawal latency tests were performed. After administration, the L4, L5 dorsal root ganglia (DRG) neurons of rats were isolated. In addition, hyperpolarization-activated cyclic nucleotide-gated (HCN) channels subtype plasmids were transfected into human embryonic kidney (HEK)293 cells. Whole-cell clamp recordings were used to examine the properties of HCN currents (Ih) expressed in HEK293 cells and DRG neurons. After surgery, the paw withdrawal threshold to mechanical stimulation and thermal withdrawal latency were reduced, the HCN currents (Ih) amplitude of DRG neurons was increased, and the semiactivated voltage (V1/2) value was decreased in CCI rats (P
Example sentence:

We have tested the hind paw withdrawal latency (PWL) to thermal stimulation and the hind paw withdrawal threshold (PWT) to mechanical stimulation.

Peer comment(s):

agree Filippe Vasconcellos de Freitas Guimarães
14 mins
Thanks
agree Hernan Casasbuenas : I think to you are right
10 hrs
Thanks
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4 KudoZ points awarded for this answer. Comment: "Parece que sí, que es el mismo texto. Muchas gracias. "
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