Glossary entry (derived from question below)
Russian term or phrase:
10ТД
English translation:
10 therapeutic doses
- The asker opted for community grading. The question was closed on 2014-02-17 15:54:11 based on peer agreement (or, if there were too few peer comments, asker preference.)
Feb 14, 2014 14:28
10 yrs ago
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Russian term
United Kingdom
Cito, non temere
Native in: English 
Works in: German to English, Spanish to English, Russian to English, and 1 more.
10ТД
Russian to English
Medical
Biology (-tech,-chem,micro-)
I'm translating a text on lab research. The phrase is as follows:
вводили ... при помощи зонда в дозах 30 мг/кг (10ТД) и 300 мг/кг (100ТД).
What is "10ТД" in this context?
Many thanks,
Julia
вводили ... при помощи зонда в дозах 30 мг/кг (10ТД) и 300 мг/кг (100ТД).
What is "10ТД" in this context?
Many thanks,
Julia
Proposed translations
(English)
| 4 +3 | 10 therapeutic doses |
Oleksandr Kupriyanchuk
|
References
| ТД = терапевтическая доза |
Oleksandr Kupriyanchuk
|
Proposed translations
+3
27 mins
Oleksandr Kupriyanchuk
United States
United States
Native in Russian
&
English
Works in field
United States
Eng-Ukr-Rus-Fr-Pol, Tech&Sci, Legal, Med
Native in: Russian , Ukrainian , English 
Works in: Russian to English, Ukrainian to English, French to English, and 14 more.
Related KudoZ points
:
4
Russian term (edited):
10 ТД
Selected
10 therapeutic doses
Please see the reference information below.
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Note added at 31 mins (2014-02-14 15:00:20 GMT)
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LDN fills all the requirements for safety and efficacy in ameliorating a large proportion of auto immune disease.
*******It has been tested at doses 10 times therapeutic dose and found safe.******* It has been in field use for more than 25 years. There are clinical studies, double blind placebo, in Crohn's Disease and Fibromyalgia documenting efficacy in diseases thought to have auto immune mechanisms.
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Note added at 36 mins (2014-02-14 15:04:49 GMT)
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"Therapeutic doses of theophylline exert proconvulsant effects in developing mice."
Authors: Yokoyama H, Onodera K, Yagi T, Iinuma K.
Brain & development, September 1997, vol./is. 19/6(403-7), 0387-7604.
(available as free previews)
"We studied the effect of therapeutic doses of theophylline on electrically-induced convulsions in developing mice... ..."
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Note added at 39 mins (2014-02-14 15:08:44 GMT)
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Lippincott's Manual of Toxicology
http://books.google.com.ua/books/about/Lippincott_s_Manual_o...
Activated charcoal should be considered in all patients with recent intentional overdose of more than *******10 therapeutic doses*******
Etc., etc.
--------------------------------------------------
Note added at 31 mins (2014-02-14 15:00:20 GMT)
--------------------------------------------------
LDN fills all the requirements for safety and efficacy in ameliorating a large proportion of auto immune disease.
*******It has been tested at doses 10 times therapeutic dose and found safe.******* It has been in field use for more than 25 years. There are clinical studies, double blind placebo, in Crohn's Disease and Fibromyalgia documenting efficacy in diseases thought to have auto immune mechanisms.
--------------------------------------------------
Note added at 36 mins (2014-02-14 15:04:49 GMT)
--------------------------------------------------
"Therapeutic doses of theophylline exert proconvulsant effects in developing mice."
Authors: Yokoyama H, Onodera K, Yagi T, Iinuma K.
Brain & development, September 1997, vol./is. 19/6(403-7), 0387-7604.
(available as free previews)
"We studied the effect of therapeutic doses of theophylline on electrically-induced convulsions in developing mice... ..."
--------------------------------------------------
Note added at 39 mins (2014-02-14 15:08:44 GMT)
--------------------------------------------------
Lippincott's Manual of Toxicology
http://books.google.com.ua/books/about/Lippincott_s_Manual_o...
Activated charcoal should be considered in all patients with recent intentional overdose of more than *******10 therapeutic doses*******
Etc., etc.
4 KudoZ points awarded for this answer.
Comment: "Thank you."
Reference comments
21 mins
Oleksandr Kupriyanchuk
United States
United States
Native in Russian
&
English
Works in field
United States
Eng-Ukr-Rus-Fr-Pol, Tech&Sci, Legal, Med
Native in: Russian , Ukrainian , English
Works in: Russian to English, Ukrainian to English, French to English, and 14 more.
Related KudoZ points
:
4
Reference:
ТД = терапевтическая доза
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
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Note added at 22 mins (2014-02-14 14:50:50 GMT)
--------------------------------------------------
"ТД – терапевтическая доза
...
Изучили мутагенное действие фармакологической субстанции киллевир-16 методом учета хромосомных аберраций в клетках костного мозга мышей C57Bl/6 при четырехкратном пероральном введении в эквитерапевтической дозе (1 ТД) и десятикратно её превышающей (10 ТД). Дозы для животных рассчитаны по соотношению площади поверхности тела человека и мыши: терапевтическая доза для человека – 40 мг, для мыши 1 ТД=0,13 мг на особь, 10 ТД=1,33 мг на особь. Каждая экспериментальная группа представлена пятью самцами и пятью самками."
--------------------------------------------------
Note added at 22 mins (2014-02-14 14:50:50 GMT)
--------------------------------------------------
"ТД – терапевтическая доза
...
Изучили мутагенное действие фармакологической субстанции киллевир-16 методом учета хромосомных аберраций в клетках костного мозга мышей C57Bl/6 при четырехкратном пероральном введении в эквитерапевтической дозе (1 ТД) и десятикратно её превышающей (10 ТД). Дозы для животных рассчитаны по соотношению площади поверхности тела человека и мыши: терапевтическая доза для человека – 40 мг, для мыши 1 ТД=0,13 мг на особь, 10 ТД=1,33 мг на особь. Каждая экспериментальная группа представлена пятью самцами и пятью самками."
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