Glossary entry

French term or phrase:

anti-antegrine (or: anti-corps anti-integrine)

English translation:

anti-integrin (integrin antibody)

Added to glossary by Rachel Fell
Mar 17, 2008 11:19
16 yrs ago
1 viewer *
French term

anti-antegrine

French to English Medical Medical (general) medical report on cancer patient
This is describing the kind of drugs being used
'anti-corps anti-integrine' (with acute accent on first 'e')
Proposed translations (English)
3 +4 anti-integrin
4 +4 anti-integrin
Change log

Mar 22, 2008 09:25: mportal Created KOG entry

Mar 22, 2008 09:54: Rachel Fell changed "Edited KOG entry" from "<a href="/profile/55046">mportal's</a> old entry - "anti-antegrine"" to ""anti-integrin""

Proposed translations

+4
12 mins
French term (edited): anti-antegrine > anti-integrine
Selected

anti-integrin

seems to be this

Journal of Translational Medicine | Full text | A function ...
Affinities between α5β1-Fc and anti-integrin antibodies were analyzed using a BIAcore 3000 essentially as described [26,27]. Goat anti-rat Fc antibodies ...
www.translational-medicine.com/content/5/1/61 - 95k

Leukocyte recruitment to inflammation sites depends on interactions between integrins and extracellular matrix (ECM). In this report we show that mice lacking the ECM protein mindin exhibit severely impaired recruitment of neutrophils and macrophages in 4 different inflammation models. Furthermore, neutrophils directly bind to immobilized mindin, and mindin matrix mediates neutrophil migration in vitro. The adhesion of neutrophils to mindin is blocked by anti–integrin α4, anti–integrin αM, and anti–integrin β2 antibodies. We also show that HEK-293 cells transfected with cDNA encoding these integrins exhibit enhanced binding to immobilized mindin matrix and the increased binding can be blocked by anti-integrin antibodies. Our results suggest that mindin serves as a novel ligand for integrins and mindin-integrin interactions are critical for inflammatory cell recruitment in vivo.

http://ukpmc.ac.uk/articlerender.cgi?artid=1004440

Trichuris muris : CD4 + T cell-mediated protection in ...
saturating levels of anti-integrin antibodies (Picarella. Parasitology (2000), 121, 631–637. Printed in the United Kingdom " 2000 Cambridge University Press ...
journals.cambridge.org/production/action/cjoGetFulltext?fulltextid=73462

Kidney International - Internalization of antibodies by ...
(C) Blocking effect of anti-integrin beta 1 antibody on the internalization of 17H8a antibodies. HUVECs were cultured with FITC-17H8a antibodies for 4 hours ...
www.nature.com/ki/journal/v64/n5/full/4494072a.html
Peer comment(s):

agree Isabelle Berquin
24 mins
Thanks, Isabelle:-)
agree Cetacea : or just "integrin antibodies"; see e.g. http://www.scbt.com/table-integrin.html I know "anti-integrin antibodies" is commonly used as well, but one "anti" always seems enough for me... ;-)
1 hr
Thank you Cetacea;-)
agree Helen Genevier
1 hr
Thank you Helen:-)
agree sktrans
3 hrs
Thank you sktrans:-)
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thanks very much, Rachel "
+4
12 mins

anti-integrin

antibodies against integrin
Example sentence:

The adhesion of neutrophils to mindin is blocked by anti-integrin α[4], anti-integrin α[M], and anti-integrin β[2] antibodies.

Peer comment(s):

agree Isabelle Berquin
24 mins
thanks Isabelle
agree Cetacea : or just "integrin antibodies"; see e.g. http://www.scbt.com/table-integrin.html I know "anti-integrin antibodies" is commonly used as well, but one "anti" always seems enough for me... ;-)
1 hr
agree Helen Genevier
1 hr
Thanks ;-)
agree sktrans
3 hrs
Thanks ;-)
Something went wrong...
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