Glossary entry (derived from question below)
English term or phrase:
Low Affinity
English answer:
Dorlands Medical Dictionary says..
Added to glossary by
Rafaqat Dogar
Mar 15, 2004 08:14
20 yrs ago
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English term
United Kingdom
More than 18 Years in Translation Field
Native in: Urdu 
Works in: English to Urdu, Punjabi to English, Urdu to English, and 2 more.
Low Affinity
English
Medical
Medical: Pharmaceuticals
Pharmacodynamic properties
The sentence is as follow:
As a result saquinavir fits closely into the HIV-1 proteinase active sites, in vitro acting as a reversible and selective inhibitor, with approximately a 50,000-fold lower affinity for human proteinases.
Thanks a lot.
As a result saquinavir fits closely into the HIV-1 proteinase active sites, in vitro acting as a reversible and selective inhibitor, with approximately a 50,000-fold lower affinity for human proteinases.
Thanks a lot.
Responses
| 2 +5 | Dorlands Medical Dictionary says.. |
Jonathan MacKerron
|
Responses
+5
3 mins
Jonathan MacKerron
Native in English
&
English
Specializes in field
Retired as of Jan 2019!
Native in: English
Works in: German to English, French to English
Related KudoZ points
:
20
Selected
Dorlands Medical Dictionary says..
"1. a special attraction for a specific element, organ, or structure. 2. chemical a. 3. in immunology, a thermodynamic pression of the strength of interaction between a single antigen-binding site and a single antigenic determinant (and thus of the stereochemical compatibility between them), most accurately applied to interactions among simple, uniform antigenic determinants such as haptens. Expressed as the association constant (K liters mole-1), which, owing to the heterogeneity of affinities in a population of antibody molecules of a given specificity, actually represents an average value (mean intrinsic association constant)."
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Note added at 4 mins (2004-03-15 08:18:51 GMT)
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\"causal relationship\"
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Note added at 10 mins (2004-03-15 08:24:56 GMT)
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for chemical affinity Dorlands adds \"the tendency of an atom or compound to combine by chemical reaction with atoms or compounds of unlike composition\"
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Note added at 4 mins (2004-03-15 08:18:51 GMT)
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\"causal relationship\"
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Note added at 10 mins (2004-03-15 08:24:56 GMT)
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for chemical affinity Dorlands adds \"the tendency of an atom or compound to combine by chemical reaction with atoms or compounds of unlike composition\"
4 KudoZ points awarded for this answer.
Comment: "Thank you indeed."
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