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Nov 9, 2023 18:29
6 mos ago
24 viewers *
French term

sensible à forte posologie aux ipenèmes

French to English Medical Medical (general) ipenèmes
Hi,

In a patient's hospital report, it says they are 'sensible à forte posologie aux ipenèmes.' I can't find the latter term and wonder if it is a misspelling? Does anyone have any advice?

Thank you.
Proposed translations (English)
4 +1 sensitive/susceptible to penems in high concentrations
4 +2 susceptible to high-dose treatment with imipenem
4 Imipenem
References
see:

Discussion

Drmanu49 Nov 11, 2023:
Sensitive is a false friend Phil.
philgoddard Nov 10, 2023:
Drmanu You've misread Anton's answer, and your disagree is wrong. He doesn't say 'sensible'.
Bashiqa Nov 9, 2023:
@ Asker If your first attempt does not find anything then try ipenem; medication.
google will usually propose something very close to the misspelling and with the contaxt you have, you should be able to find the answer.

Proposed translations

+1
5 hrs
Selected

sensitive/susceptible to penems in high concentrations

Note the plural, it denotes a whole group of antibiotics known as penems. Some of these also have an "i" preceding the suffix: imipenem, doripenem, panipenem, ritipenem. To be more precise, these four actually belong to two related drug families: penems and carbapenems, so you may want to write "penems/carbapenems" instead of just "penems".
The usual pathogens targeted by these antibiotics are Pseudomonas spp.
Peer comment(s):
neutral philgoddard : This would explain why it's 'ipenèmes' in the plural, but I don't understand your explanation and you haven't given references. Do you mean it's a typo for 'pénèmes'?//. And you clearly don't know what 'typo' means. There's no need to be so rude.
8 hrs
It's a misspelling rather than a typo. Sorry to be blunt, but you don't understand the explanations precisely because you don't know medicine in general and pharmacology in particular.
disagree Drmanu49 : Certainly not sensitive which is a false friend.
8 hrs
"sensitive" and "susceptible" in this context are interchangeable
agree liz askew : https://mft.nhs.uk/app/uploads/2020/10/Antimicrobial-Suscept...
1 day 17 hrs
agree Anastasia Kalantzi
7 days
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you, Anton. I appreciate your expertise!"
9 mins

Imipenem

Imipenem, def below

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Note added at   11 min (2023-11-09 18:41:17 GMT)
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examples
https://pubmed.ncbi.nlm.nih.gov/3460521/
https://pubmed.ncbi.nlm.nih.gov › 33545803
https://academic.oup.com › jac › article › 58 › 5 › 916 › 740065
Reference:

https://en.wikipedia.org/wiki/Imipenem

Something went wrong...
+2
8 mins

susceptible to high-dose treatment with imipenem

Safety and efficacy of high-dose treatment with imipenem ...
National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
·
Traduire cette page
de BA Zajac · 1985 · Cité 32 fois — Imipenem-cilastatin was given in doses of 1 g intravenously every 6 h to 31 patients. Twenty-five patients, with 27 infections, were clinically evaluable ...


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Note added at 9 minutes (2023-11-09 18:39:18 GMT)
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Imipenem - an overview | ScienceDirect Topics
ScienceDirect
https://www.sciencedirect.com › im...
·
Traduire cette page
Imipenem is a more common cause of seizures than other beta-lactam antibiotics, particularly when high doses are given [28C,29AR]. Since imipenem + cilastatin ...



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Note added at 1 jour 15 heures (2023-11-11 10:14:20 GMT)
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Carbapenems: Past, Present, and Future - PMC
National Institutes of Health (.gov)
https://www.ncbi.nlm.nih.gov › pmc
de KM Papp-Wallace · 2011 · Cité 1668 fois — We describe the initial discovery and development of the carbapenem family of β-lactams. Of the early carbapenems evaluated,
Note from asker:
Following additional research, it seems this is the most likely meaning. Thank you!
Peer comment(s):
agree Anastasia Kalantzi
2 hrs
Thank you.
agree Daryo
1 day 2 hrs
Thank you.
neutral philgoddard : But it's in the plural.
1 day 12 hrs
Imipenem belongs to the carbapenem family so it either means susceptible to carbapenems or to imipenem.
Something went wrong...

Reference comments

1 day 22 hrs
Reference:

see:

http://apha.defra.gov.uk/ahvla-scientific/vetqas/PT0092.html

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Note added at 1 Tag 22 Stunden (2023-11-11 17:15:40 GMT)
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https://medlineplus.gov/lab-tests/antibiotic-sensitivity-tes...
Something went wrong...
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