Glossary entry (derived from question below)
English term or phrase:
fixed class effect terms for treatment
English answer:
fixed-effect class variables
Added to glossary by
V&E-Team
Sep 9, 2017 18:40
6 yrs ago
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English term
fixed class effect terms for treatment
English
Medical
Mathematics & Statistics
clinical trial/statistical method
Hello,
Could you please help me analise/parse this EN phrase:
-fixed class effect terms for treatment
I mean, describe it in other EN words or express yourself differently.
Context: Clinical trial/statistical method
The primary efficacy analysis will be performed by fitting a mixed-effect model repeated measure (MMRM) analysis with an unstructured variance covariance structure in which the change from the baseline in YMRS Total Score during the double-blind treatment phase will be the dependent variable based on the observed cases data set.
The model will include fixed class effect terms for treatment, trial site, visit week, and an interaction term of treatment by visit week.
Thank you!
Could you please help me analise/parse this EN phrase:
-fixed class effect terms for treatment
I mean, describe it in other EN words or express yourself differently.
Context: Clinical trial/statistical method
The primary efficacy analysis will be performed by fitting a mixed-effect model repeated measure (MMRM) analysis with an unstructured variance covariance structure in which the change from the baseline in YMRS Total Score during the double-blind treatment phase will be the dependent variable based on the observed cases data set.
The model will include fixed class effect terms for treatment, trial site, visit week, and an interaction term of treatment by visit week.
Thank you!
Responses
| 3 | fixed-effect class variables |
Herbmione Granger
|
Responses
21 hrs
Herbmione Granger
Germany
Germany
Native in English
&
English
Germany
An American scholar based in Germany
Native in: English (Variant: US) 
Works in: French to English, German to English, English
Related KudoZ points
:
4
Selected
fixed-effect class variables
It looks like 'treatment', 'trial site', 'visit week', etc. are the input terms for the class variables.
'For Proc Mixed we need to specify that group, time, and subject are class variables. (See the syntax above.) This will cause SAS to treat them as factors (nominal or ordinal variables) instead of as continuous variables.' http://www.uvm.edu/~dhowell/StatPages/More_Stuff/Mixed-Model...
'A fixed-effect class variable for study year was included as a covariate in the health model' http://europepmc.org/articles/PMC4104685
'Si was a fixed effect class variable for study (experiment), Tj was a fixed effect class variable for treatment, Bik was a random class variable for study site (block)' https://academic.oup.com/forestry/article/82/5/583/617194/Ev...
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Note added at 22 hrs (2017-09-10 16:45:20 GMT)
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Edit: 'Treatment', 'trial site' and 'visit week' correspond to fixed-effect class variables. 'Treatment by visit week' corresponds to an interaction term.
'For Proc Mixed we need to specify that group, time, and subject are class variables. (See the syntax above.) This will cause SAS to treat them as factors (nominal or ordinal variables) instead of as continuous variables.' http://www.uvm.edu/~dhowell/StatPages/More_Stuff/Mixed-Model...
'A fixed-effect class variable for study year was included as a covariate in the health model' http://europepmc.org/articles/PMC4104685
'Si was a fixed effect class variable for study (experiment), Tj was a fixed effect class variable for treatment, Bik was a random class variable for study site (block)' https://academic.oup.com/forestry/article/82/5/583/617194/Ev...
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Note added at 22 hrs (2017-09-10 16:45:20 GMT)
--------------------------------------------------
Edit: 'Treatment', 'trial site' and 'visit week' correspond to fixed-effect class variables. 'Treatment by visit week' corresponds to an interaction term.
4 KudoZ points awarded for this answer.
Comment: "thank you"
Discussion
And I think 'class' refers to the class of antidepressant treatments:
'Treatment options following inadequate response to ADT include dose adjustments, switching to another ADT (either within the same class or in another ADT class)'
'Fixed terms for treatment' is quite clear, it's 'class effect' that stumps me. Effects ON class, effects OF class?